Movement Disorders (revue)

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Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism : First case report

Identifieur interne : 003A61 ( Main/Exploration ); précédent : 003A60; suivant : 003A62

Preserved myocardial [123I]metaiodobenzylguanidine uptake in autosomal recessive juvenile parkinsonism : First case report

Auteurs : Masahiko Suzuki [Japon] ; Nobutaka Hattori [Japon] ; Satoshi Orimo [Japon] ; Nobuyoshi Fukumitsu [Japon] ; M. Masahiro Abo [Japon] ; Yu Kono [Japon] ; Renpei Sengoku [Japon] ; Akira Kurita [Japon] ; Hidehiko Honda [Japon] ; Kiyoharu Inoue [Japon]

Source :

RBID : Pascal:05-0281352

Descripteurs français

English descriptors

Abstract

A decrease in myocardial uptake of iodine-123-labeled metaiodobenzylguanidine (123I-MIBG) has been reported in idiopathic Parkinson's disease (PD) using 123I-MIBG myocardial scintigraphy. However, the patient with autosomal recessive juvenile parkinsonism (AR-JP). caused by the parkin gene, presented here showed normal 123I-MIBG myocardial uptake, suggesting that AR-JP is a distinct disease entity from PD. Although the clinical features of AR-JP are sometimes quite similar to those of late-onset idiopathic PD. 123I-MISG myocardial scintigraphy may be a powerful tool to differentiate PD from other parkinsonian syndromes, including AR-JP.


Affiliations:


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Le document en format XML

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<name sortKey="Fukumitsu, Nobuyoshi" sort="Fukumitsu, Nobuyoshi" uniqKey="Fukumitsu N" first="Nobuyoshi" last="Fukumitsu">Nobuyoshi Fukumitsu</name>
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<series>
<title level="j" type="main">Movement disorders</title>
<title level="j" type="abbreviated">Mov. disord.</title>
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<term>Parkinsonism</term>
<term>Uptake</term>
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<keywords scheme="Pascal" xml:lang="fr">
<term>Système nerveux pathologie</term>
<term>Parkinsonisme</term>
<term>Parkinson maladie</term>
<term>Captation</term>
<term>Etude cas</term>
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<front>
<div type="abstract" xml:lang="en">A decrease in myocardial uptake of iodine-123-labeled metaiodobenzylguanidine (
<sup>123</sup>
I-MIBG) has been reported in idiopathic Parkinson's disease (PD) using
<sup>123</sup>
I-MIBG myocardial scintigraphy. However, the patient with autosomal recessive juvenile parkinsonism (AR-JP). caused by the parkin gene, presented here showed normal
<sup>123</sup>
I-MIBG myocardial uptake, suggesting that AR-JP is a distinct disease entity from PD. Although the clinical features of AR-JP are sometimes quite similar to those of late-onset idiopathic PD.
<sup>123</sup>
I-MISG myocardial scintigraphy may be a powerful tool to differentiate PD from other parkinsonian syndromes, including AR-JP.</div>
</front>
</TEI>
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